LEADER 02154nam  2200205 n 450 
001 TD13052171
049   $aTDMAGDIG
100   $a20190501d2009------k--ita-50----ba 
200 1 $aNatural and Unnatural History of Isolated Ventricular Septal Defects in a Paediatric Population: A Longitudinal Retrospective Study$bTesi di dottorato
300   $aIn relazione con http://paduaresearch.cab.unipd.it/1511/
328  0$btesi di dottorato$cMED/38 Pediatria generale e specialistica
330   $aThis study shows the rate of spontaneous closure of various types of ventricular septal defects over time, 519 patients with VSD had been studied and followed by time, the spontaneous closure(SC) had been documented in 80% (185/232) of all muscular defects, in 22%(62/279) of perimembranous defects, one case(1/8, 12%) of subpolmonary defects. the SC  had been registered in 19 of patients by age of 6 months, in 50% of cases by age between 1-2 years , in 77 % of patients between 2-4 years , and in 97 % by age between 6 and 10 years. in patients without congestive heart failure(CHF), the rate  of SC was 50%, the SC had been registered in (12/74) 16% of patients with CHF. this observation suggest un conservative attitude in the first months of life, unless a pulmonary hypertension is  developed. surgery is quite safe ( we haven?t considered the per operative mortality), although sever complications like complete a-v block was verified  in 2% of cases, VSD residual in 14% of cases with the necessity of re-intervention in 1% of cases , we contend that the SC, probably, occur by the growth of muscular septum around the defect, this explain why muscular defects close before membranous VSD, like we have demonstrated in our study. 
336   $aapplication/pdf
689 0 $aMED/38$bPediatria generale e specialistica$cTDR
700  0$aAhmad, Ammar
801  3$aIT$bIT-FI0098
856 4 $uhttp://memoria.depositolegale.it/*/http://paduaresearch.cab.unipd.it/1511/1/Copia_finale_di_tesi_da_stampare_corretta%5B1%5D.pdf$2http://paduaresearch.cab.unipd.it/1511/1/Copia_finale_di_tesi_da_stampare_corretta%5B1%5D.pdf
997   $aCF
FMT   $aTD
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