Sagheddu, Claudia
Functional characterization of molecular candidates for the calcium-activated chloride channels in the cilia of olfactory sensory neurons [Tesi di dottorato]
SISSA, 2011-11-10T07:38:38Z
Olfactory sensory neurons (OSNs) use a Ca2+-activated Cl? channels amplification mechanism in olfactory transduction. Odor binding to odorant receptors in the cilia of OSNs leads to an increase of intraciliary Ca2+ concentration by Ca2+ entry through cyclic nucleotide-gated channels. Ca2+ activates a Cl? channel that leads to an efflux of Cl? from the cilia, contributing to the depolarization in OSNs....
Menini, Anna
Neurobiology
Neuroscience


Tesi di dottorato. | Lingua: en. | Paese: | BID: TD15087922