The purpose of this research is to go over and to examine the history of Milan’s nunnery of Visitation, called Santa Sofia, between 18th and 19th century. The large amount of documents kept into the archive of the convent allowed to investigate many aspects, especially those concerning the bonds with the others convents of the same order and with the Milan’s society. Other important aspects investigated are those concerning the nuns' relationships with the political power and the analysis of religious practices and cultural aspects. From the middle 18th century Santa Sofia joined in the wide-ranging process of catholic missionary openness.